Interactive FAQs Male Factor Infertility Question: My husband submitted a semen specimen, the results were that no sperm was present in the specimen. There is no medical reason for this, he has not had an ilness or been on drugs, he doesn't smoke or drink alcohol. We have been told it may be a blockage, what I don't understand is that he hasn't had any symptoms, If it were a blockage is there any symptoms or any way we could have known? If no sperm is found, is our only option donor? Renee V. Australia Answer Rarely are there any preceding symptoms to explain why no sperm are detected in the semen analysis. While obstruction can result from infection, most often these infections are asymptomatic and the first clue is the abnormal semen analysis. The urologist will perform a complete medical history and physical exam and may also wish to measure blood testosterone and FSH levels. Sperm antibodies, and genetic testing for cystic fibrosis carrier status may also be recommended. The final step is the testicular biopsy. Make sure that if sperm are detected at the time of biopsy, the lab is prepared to freeze a specimen to be available should you desire IVF with sperm injection in the future. (www.ivf.com/insem.html) Dr. Perloe FAQ archives: IVF PCOS Clomiphene Ovulation Ovulation Induction Injections Age Related Infertility Endometriosis Donor Egg Donor Sperm Fallopian Tube Reanastomosis Tubal Infertility Unexplained Infertility Endometrial Factor Miscellaneous Return to the IVF Homepage This page, and all contents, are Copyright © 2003 by IVF.com, Atlanta, GA, USA.